Envita Medical Centers
Chemo Immuno Precision Injections

Precision-guided treatment —delivered straight into the tumor.

Image guidanceTargeted access

Standard chemo travels through the whole body. Envita's CIPI™ procedure is different: it delivers treatment made for your exact tumor, right where it's needed, then helps keep it there.

Experience
25 years
Location
Scottsdale, AZ
Advantages
Targets the tumor directly
Why so much treatment fails to reach the tumor

Tumor structure can affect drug penetration

Dense, complex tumors can present a challenge for drug delivery. In pancreatic cancer, surrounding fibrous tissue may limit chemotherapy penetration, while intravenous treatment continues to circulate throughout the rest of the body.

Traditional IV chemotherapy

Circulates throughout the body, not only the tumor.

  • Healthy tissue may also be affected.
  • Drug penetration can vary within solid tumors.
  • Treatment-related side effects can limit dosing.
CIPI™ Precision Injection

Deliver the dose inside the tumor. Then seal it in.

  • Image guidance supports precise access to the targeted treatment area.
  • A micro-dosed, genetically-targeted combination is injected at the source.
  • The tumor's blood supply is sealed off to hold the medication in place.
Inside the procedure · EnvitaIR™

How a Chemo Immuno Precision Injection actually works.

CIPI™ may use an image-guided catheter-based approach or a percutaneous injection through the skin. Both are minimally invasive approaches intended to deliver treatment directly to the targeted area.

  1. 01

    We read your cancer's genetics first

    Before anything is delivered, we examine your miRNA, circulating tumor cell DNA, and tumor mutations—mapping the specific targets found in both your tumor and your unique genetic make-up.

  2. 02

    Our in-house pharmacy builds your dose

    Envita's custom pharmacy formulates a personalized combination of genetically-targeted medications with adjunctive agents chosen to potentially enhance how the drugs act with the goal of upregulating your own immune system.

  3. 03

    We select an image-guided access approach

    Depending on individual clinical and anatomical factors, treatment may be delivered through a small, precisely positioned catheter or by percutaneous injection through the skin directly into the targeted treatment area.

  4. 04

    Treatment is delivered to the targeted area

    The selected medication is delivered directly to the treatment area. When a catheter-based approach is used, the physician may also embolize blood flow to help keep the medication focused at the site. The appropriate approach is determined through individual clinical evaluation.

Virtual procedure walkthrough
Envita's treatment selection process

A personalized approach to image-guided, tumor-directed treatment.

Before treatment is delivered, CIPI™ uses genomic and molecular information to help guide an individualized treatment plan and the appropriate image-guided access approach.

Genomically targeted

Chemo-genetic and immune-genetic targets are drawn from your tumor + your DNA, not a one-size protocol.

Immune-activating

Designed to potentially upregulate your immune system so it can help seek out circulating cancer cells.

Minimally invasive

Image-guided access using either a small, precisely positioned catheter or a percutaneous injection through the skin, designed to deliver targeted therapeutic agents directly to the treatment area without open surgery.

Who CIPI™ was designed for

When standard care isn't enough—and surgery isn't an option.

CIPI™ may be evaluated for certain patients with solid tumors, including patients who have previously received other therapies or who may not be surgical candidates.

Four common candidacy profiles
  • 01
    Dense, hard-to-treat cancersPancreatic, liver, and other solid tumors IV chemo struggles to penetrate.
  • 02
    Surgery isn't viableWhen an operation would stress the body or suppress the immune system too much.
  • 03
    You've failed other therapiesWhen the standard-of-care protocol hasn't been enough and you need precision options.
  • 04
    Complex or advanced-stage cancerWhere precise, targeted delivery matters more than a maximum systemic dose.
When you've been told your options are running out, precision stops being a luxury. It becomes the whole point.
The idea behind CIPI™ · Envita Medical Centers
Take the first step

Find out if CIPI™ could be an option for your cancer.

Answer a few questions and our team will review whether you may be a candidate for a Chemo Immuno Precision Injection.

Takes about 90 seconds · Reviewed by Envita's care team

Important medical & treatment information

The information on this page is provided for general educational and informational purposes only and is not intended to provide medical advice, establish a standard of care, or replace consultation with a qualified healthcare professional. Individual treatment decisions should be made by a licensed healthcare provider based on each patient's medical history, diagnosis, condition, treatment history, diagnostic testing, and other relevant clinical factors.

Chemo Immuno Precision Injections (CIPI™) is Envita Medical Centers' proprietary approach to individualized, image-guided, tumor-directed treatment. CIPI™ is not appropriate or available for every patient, cancer type, tumor, or clinical circumstance. Eligibility is determined on an individual basis following medical evaluation. Certain patients may not have appropriate anatomical, clinical, genomic, molecular, or other characteristics necessary for treatment.

Descriptions of CIPI™ mechanisms, treatment selection, tumor-directed delivery, molecular or genomic targeting, embolization, immune-related treatment strategies, or other potential treatment objectives describe the intended approach and goals of treatment and should not be interpreted as a representation, promise, or guarantee of a particular biological response or clinical outcome.

Envita Medical Centers does not guarantee treatment response, tumor reduction, remission, cure, survival, increased life expectancy, prevention of recurrence or metastasis, improvement in symptoms or quality of life, or any other specific outcome. Results vary substantially among patients, and some patients may receive no clinical benefit or may experience disease progression despite treatment.

Any patient experiences, testimonials, case examples, or treatment outcomes presented on this website describe the experiences of individual patients. Individual results vary, and these experiences should not be interpreted as typical, expected, or guaranteed results for other patients.

CIPI™ treatment plans may incorporate prescription medications, chemotherapy agents, compounded medications, adjunctive agents, and/or other therapies selected by a treating physician according to the individual patient's clinical circumstances. Some uses of medications or combinations of medications may differ from FDA-approved labeling. Compounded drugs are not FDA-approved, and the FDA does not review compounded drugs for safety, effectiveness, or quality before they are marketed.

Information comparing CIPI™ with conventional chemotherapy, surgery, embolization, or other cancer treatments is provided to explain differences in treatment approaches and is not intended to establish that CIPI™ is safer, more effective, or clinically superior to standard-of-care treatment. The risks, benefits, alternatives, and appropriateness of any treatment must be evaluated individually with a qualified healthcare professional.

Cancer treatment involves significant risks. CIPI™ and medications or procedures used in connection with it may cause adverse effects, complications, or other risks. The nature and likelihood of these risks depend on the patient's condition and treatment plan and should be discussed with the treating physician before treatment.

Do not delay, discontinue, replace, or modify standard medical care based on information contained on this website. Patients should consult their oncologist or other qualified healthcare professional before making decisions regarding cancer treatment, including changing or stopping chemotherapy, radiation therapy, surgery, immunotherapy, targeted therapy, or any other recommended treatment.

CIPI™ and EnvitaIR™ are trademarks of Envita Medical Centers.